The drug Evista (generic name raloxifene) acts like estrogen in certain places in the body, but is not a hormone.
Raloxifene is a selective estrogen receptor modulator (SERM) that is prescribed in females only, but its use in male subjects is increasingly considered. With a growing number of patients having potential benefit from raloxifene, the need for an assessment of its effects on brain function is growing. Effects of estrogens on brain function are very subtle and difficult to detect by neuropsychological assessment. Functional imaging techniques, however, have been relatively successful in detecting such changes. This study used functional magnetic resonance imaging (fMRI) to examine effects of raloxifene treatment on memory function. Healthy elderly males (n = 28; mean age 63.6 years, SD 2.4) were scanned during performance on a face encoding paradigm. Scans were made at baseline and after 3 months of treatment with either raloxifene (n = 14) or placebo (n = 14). Treatment effects were analyzed using mixed-effects statistical analysis (FSL). Activation during task performance involved bilateral parietal and prefrontal areas, anterior cingulate gyrus, and inferior prefrontal, occipital, and mediotemporal areas bilaterally. When compared to placebo, raloxifene treatment significantly enhanced activation in these structures (Z > 3.1), except for mediotemporal areas. Task performance accuracy diminished in the placebo group (P = 0.02), but remained constant in the raloxifene group (P = 0.60). In conclusion, raloxifene treatment enhanced brain activation in areas spanning a number of different cognitive domains, suggesting an effect on cortical arousal. Such effects may translate into small effects on behavior, including effects on attention and working memory performance, executive functions, verbal skills, and episodic memory. Further neuropsychological assessment is necessary to test the validity of these predictions.
Friday 20 March 2009
Monday 16 February 2009
Evista medicine
Evista Prevents Osteoporosis In Postmenopausal Women
Evista is the brand name for raloxifene. Evista is manufactured by the Eli Lilly Corpora
tion.
Evista was developed for the treatment and prevention of osteoporosis in postmenopausal women. Therefore, those who should NOT take this drug are those women who can still become pregnant, are pregnant, or are nursing.
Raloxifene prevents bone loss and increases bone mineral density. In studies, raloxifene increased calcium levels related to hip and spine bone mineral density within 1 year, maintaining those levels for 2. Subjects who took calcium only lost 1% of their bone mineral density related calcium during the same time period.
Evista is one of the best options available for the treatment of osteop
orosis and is also considered as a safe drug. But since all the medications have some kind of side effects it is also the case with Evista. Some side effects are bound to occur in some women during the treatment. Side effects that can be caused by Evista are well documented and it implies that it causes birth defects in an unborn baby. Other than this some other complications that can be administered while taking Evista are blood clot formations, swelling of the legs, sudden chest pain, coughing up blood, changes in vision. If one finds any such complications during the treatment she should immediately seek the medical attention.
Evista is the only second FDA approved drug, which is used to reduce the risk of breast cancer. It is commonly referred to as a selective estrogen receptor modulator (SERM). Evista is currently taken by about half a million women in the U.S. to prevent and treat osteoporosis, or thinning of the bones. Researchers had previously observed lower rates of breast cancer in women taking Evista than in the general population. Evista is taken once each day and it can be taken any time of the day. One should avoid alcohol and tobacco while taking Evista and should do weight bearing exercises to strengthen her bones.
One of the best ways to buy Evista is through online drug store where one can avail fabulous discounts on the purchase. Moreover one can order this medication online by just sitting at home and the medication will be delivered at home. It has become an easy and fast process of availing best medication at the reasonable price.
Evista is the brand name for raloxifene. Evista is manufactured by the Eli Lilly Corpora
tion.Evista was developed for the treatment and prevention of osteoporosis in postmenopausal women. Therefore, those who should NOT take this drug are those women who can still become pregnant, are pregnant, or are nursing.
Raloxifene prevents bone loss and increases bone mineral density. In studies, raloxifene increased calcium levels related to hip and spine bone mineral density within 1 year, maintaining those levels for 2. Subjects who took calcium only lost 1% of their bone mineral density related calcium during the same time period.
Evista is one of the best options available for the treatment of osteop
orosis and is also considered as a safe drug. But since all the medications have some kind of side effects it is also the case with Evista. Some side effects are bound to occur in some women during the treatment. Side effects that can be caused by Evista are well documented and it implies that it causes birth defects in an unborn baby. Other than this some other complications that can be administered while taking Evista are blood clot formations, swelling of the legs, sudden chest pain, coughing up blood, changes in vision. If one finds any such complications during the treatment she should immediately seek the medical attention.Evista is the only second FDA approved drug, which is used to reduce the risk of breast cancer. It is commonly referred to as a selective estrogen receptor modulator (SERM). Evista is currently taken by about half a million women in the U.S. to prevent and treat osteoporosis, or thinning of the bones. Researchers had previously observed lower rates of breast cancer in women taking Evista than in the general population. Evista is taken once each day and it can be taken any time of the day. One should avoid alcohol and tobacco while taking Evista and should do weight bearing exercises to strengthen her bones.
One of the best ways to buy Evista is through online drug store where one can avail fabulous discounts on the purchase. Moreover one can order this medication online by just sitting at home and the medication will be delivered at home. It has become an easy and fast process of availing best medication at the reasonable price.
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